Optoproteomics - Turning a Microscope into a "Microscoop"

Optoproteomics is a revolutionary technology that entirely changes your impression of a microscope, enabling protein "picking" physically at the subcellular location you are interested in on the microscope image you see.

With fully automated AI-based region recognition and high-content photochemical labeling, one can collect enough proteins for mass spectrometry-based proteomics to identify novel proteins for basic research or disease mechanism studies.

If you are interested in knowing what proteins are involved in immune cells attacking cancer cells, optoproteomics can be used to determine the components in the immune cell-cancer cell interface, i.e. immune synapse, and possibly suggest a strategy to enhance immunotherapy. There are a wide variety of problems that can be benefited by this technology. Integrating microscopy, deep learning, mechatronics, optics, photochemistry, biochemistry, and mass spectrometry with 5 years of development, optoproteomics technology is expected to be indispensable for next-generation biological research, pushing our current limit of whole cell DNA/RNA studies to a new horizon of highly-anticipated whole cell protein studies.